Featured Publications
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
Nat Med 2015; 21(7):795-801
Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion.
Science 2015; 350(6261):aac4250
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.
Nat Genet. 2016; 48:265-72
NextSeq 550 System Resources
System Literature
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Brochure | PDF | 3 versions
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Direct Bacterial Colony Sequencing with the Nextera™ DNA Flex Library Preparation KitApplication note | PDF | 1 MB
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Laboratory Experience Using Illumina Next-Generation Sequencing for Noninvasive Prenatal Testing Application NoteApplication note | PDF | < 1 MB
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Application note | PDF | 2 versions
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NextSeq 550 RNA-Seq solutionApplication note | PDF | < 1 MB
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NextSeq 550 amplicon sequencing solutionApplication note | PDF | < 1 MB
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NextSeq 550 exome sequencing solutionApplication note | PDF | < 1 MB
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QC and rebalancing of single-cell gene expression libraries using the iSeq™ 100 SystemApplication note | PDF | 2 MB
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NextSeq System Suite Installer Version 4.0 UpgradeTechnical note | HTML |
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Technical note | PDF | 2 versions
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Unify single-cell gene expression and chromatin accessibilityTechnical note | PDF | 1 MB
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Illumina CMOS Chip and One-Channel SBS Chemistrytechnology_spotlights | PDF | < 1 MB
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Direct bacterial colony sequencing with Illumina DNA PrepApplication note | PDF | < 1 MB
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Illumina DNA Prep crude lysate protocol for NGSApplication note | PDF | < 1 MB
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Technical note | PDF | 11 versions
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Explore the transcriptome with single-cell resolutionTechnical note | PDF | 1 MB
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Multiomic interrogation of the immune system at single-cell resolutionTechnical note | PDF | 1 MB
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Technical note | PDF | 9 versions
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Illumina DNA PrepData sheet | PDF | < 1 MB
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Data sheet | PDF | 5 versions
Education and Support Resources
Customer Stories
Deeper Insights on RNA Sequencing
RNA sequencing on the NextSeq 550 System provides deeper insights for this lab’s cutting-edge work in virology, moving beyond just gene expression.
View VideoBringing Bioinformatics Pipeline In-House Reduces Costs and Decreases Turnaround Time
Phosphorus uses the DRAGEN Bio-IT Platform to perform genomics data analysis onsite and at an accessible price point.
Read articleIdentifying lncRNA Biomarkers in Highly Fragmented RNA Samples
Optimizing NextSeq 500 System and TruSeq RNA Exome Kit RNA sequencing workflows for lncRNA biomarker identification.
Read article